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5,10,15,20-Tetrakis-(N-methyl-4-pyridyl)-21,23H-porphine tetratosylate


Structure: (click to enlarge, please!)

Structure of 5,10,15,20-Tetrakis-(N-methyl-4-pyridyl)-21,23H-porphine tetratosylate
Quantities Sold:  
1 g 75 €
2.5 g 150 €
5 g 270 €
10 g 510 €
Data:  
Synonym: TMPyP
Part Number: PL00630100
CAS: 36951-72-1
Molecular Formula: C72H66N8O12S4
Molecular Weight: 1363.5982
Melting Point: no information
Solubility: Water

UV/VIS-Spectrum: (click to enlarge, please!)

spectrum of 5,10,15,20-Tetrakis-(N-methyl-4-pyridyl)-21,23H-porphine tetratosylate

Informationen zum Einsatz von 

TMPyP:

This porphyrin is a potent telomerase inhibitor. In addition to its excellent suitability for antimicrobial PDT, the substance is used in fish farming as "antibiotics replacement". In analytics can be determined with TMPyP lead and copper via UV / VIS spectroscopy or HPLC.


Examples from the literature:

1.) Thandu M., Comuzzi C. and Goi D., Phototreatment of Water by Organic Photosensitizers and Comparison with Inorganic Semiconductors., International Journal of Photoenergy, , 2015, 1-22
2.) Valduga G., Breda G. M., Giacometti G. M., Jori G., and Reddi E., Photosensitation of wild and mutant strains of Escherichia coli by meso-tetra(N-methyl-4-pyridyl)porphine. , Biochemical and Biophysical Research Communication, vol. 256, no 1, 1999, 84-88
3.) Habib Md. A., Sarker A. K. and Tabata M. , Interaction of DNA with H2TMPyP4+: Probable Lead Compounds for African Sleeping Sickness., Bangladesh Pharmaceutical Journal, 17, 2014, 79-85
4.) Igarashia S., Manakaa A., Terunumaa M. and Kanekia M., Spectrophotometric Determination of Lead(II) Ion by 96-Well Microplate Electrostatically Immobilized Porphyrin., Analytical Letters, Volume 36, Issue 11, 2003, 2393-2399
5.) Feese E. and Ghiladi R. A., Highly efficient in vitro photodynamic inactivation of Mycobacterium smegmatis., J Antimicrob Chemother., 64, 2009, 782-785
6.) Camargo C. R., da Conceição Amaro Martins V., de Guzzi Plepis A. M. and Perussi J. R., Photoinactivation of Gram-Negative Bacteria in Circulating Water using Chitosan Membranes Containing Porphyrin, Biological and Chemical Research, Vol.1, Issue 2, 2014, 67-75
7.) Zamadar M., Orr C. and Uherek M., Water Soluble Cationic Porphyrin Sensor for Detection of Hg2+, Pd2+, Cd2+ and Cu2+, J. Sensors, , 2016,
8.) Malara D., Hoj L., Heimann K., Citarrella G. and Oelgemöller M., Capacity of cationic and anionic porphyrins to inactivate the potential aquaculture pathogen Vibrio campbellii, Aquaculture, 473, 2017, 228-236